Before we started Two Bit Circus, I was exploring what to work on. It turns out the absolute best use of your time is not obvious. I asked the internet and learned there are catalogs of hard problems identified to promote our happy survival and best reduce human suffering and waste.

I'm enclosing what I found in case anyone else is looking for pointers on what to do next.

• science.energy.gov — Grand Challenges
• White House OSTP Grand Challenges
• NSF Grand Challenges Task Force Report
• grandchallenges.org
• engineeringchallenges.org
• Y Combinator Requests for Startups
• a16z — 16 Things
• Millennium Prize Problems
• Global Giving SDGs
• Unsolved Math Problems
• Wikipedia — Grand Challenges
• LIGTT — 50 Breakthroughs